From concept, through design, validation, and production across all areas of your business, Pall Biopharmaceuticals can help you to adapt to changing market conditions with innovative solutions. Whether that means developing a process for a new drug quickly, validating consistent results, ensuring quality control, delivering data, or making processing easier, faster, and better, Pall is ready to address your needs with intuitive technologies.  

  • Cell Culture

    Pall's Allegro™ single use cell culture technologies are complete solutions that make your total upstream process robust and efficient, from R&D to full production scale.

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  • Chromatography

    Cost-effective and innovative chromatographic purification platforms for today’s demanding applications and productivity goals.

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  • Continuous Processing

    Breakthrough technologies that enable integrated, process-scale continuous production of biotherapies in single-use formats.

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  • Depth Filtration

    Pall's high performance depth filtration solutions are the best choice for cell harvest, clarification, and prefiltration process steps.

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  • Filling Technologies

    Flexible single-use technologies protect your product at a critical manufacturing stage.

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  • Filtration

    An unmatched portfolio of traditional and single-use products with custom service support from R&D to clinical phases to production.

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  • Single-Use Solutions

    Single-use solutions that allow easy scale-up from the lab to full cGMP commercial production.

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  • Tangential Flow Filtration

    Pall's line of scalable TFF products range from single-use modules to cleanable cassettes, and from standard lab and benchtop systems to fully customizable process systems.

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  • Viral Clearance

    A range of filters and filter capsules optimized to provide robust, economic solutions for virus removal whatever your process requirements.

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Latest Products

Learn about the latest cutting-edge Pall® products and innovative technologies to help improve, accelerate and optimize your processing steps
Learn about the latest cutting-edge Pall® products and innovative technologies to help improve, accelerate and optimize your processing steps
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INDUSTRY-LEADING PRODUCTS, SERVICES AND SUPPORT
Allegro™ MVP Single-Use System

Allegro™ MVP Single-Use System

A fully automated bioprocessing system, providing flexibility and improved productivity in upstream and downstream single-use processing.  Single-use technology continues to be adopted across many areas of bioprocessing. The use of automation provides additional benefits in manufacture such as consistency in product quality, reduced labor costs and reduction of operator errors.

Single-Use Solutions

Biomanufacturers need suppliers as innovative as they are.  Our unique single-use platform provides a comprehensive range of disposable process solutions from upstream, through downstream to formulation and filling. 

We have developed a unique approach, keeping the same materials of construction to allow easy scale-up from lab scale to full cGMP commercial operation, with the capability to provide the same robustness, reliability and batch records that you require to produce your drugs.

Biomanufacturers need suppliers as innovative as they are.  Our unique single-use platform provides a comprehensive range of disposable process solutions from upstream, through downstream to formulation and filling. 

We have developed a unique approach, keeping the same materials of construction to allow easy scale-up from lab scale to full cGMP commercial operation, with the capability to provide the same robustness, reliability and batch records that you require to produce your drugs.

We can serve our customers globally with strong technical support and a very robust and reliable supply chain with our global manufacturing platform meeting all the necessary quality requirements. We pride ourselves on the strong quality by design and ease-of-use attributes that we put into all our Allegro single-use systems, thus allowing our end users to meet consistently all the appropriate safety and regulatory requirements.    

We can serve our customers globally with strong technical support and a very robust and reliable supply chain with our global manufacturing platform meeting all the necessary quality requirements. We pride ourselves on the strong quality by design and ease-of-use attributes that we put into all our Allegro single-use systems, thus allowing our end users to meet consistently all the appropriate safety and regulatory requirements.    

Kleenpak® Presto Sterile Connector

Kleenpak® Presto Sterile Connector

Genderless sterile connections - Intuitive, reliable, secure.  The Kleenpak Presto sterile connector is the next generation in the Allegro™ range of single-use fluid handling and management devices. This new genderless connection allows for the permanent sterile connection of two fluid streams for a large range of biopharmaceutical applications.

INDUSTRY-LEADING PRODUCTS, SERVICES AND SUPPORT
Allegro™ Unison hMSCs and Media

Allegro™ Unison hMSCs and Media

Allegro Unison human mesenchymal stem cells (hMSCs) and media facilitate large scale hMSC expansion and accelerate cell therapy and regenerative medicine development. 

Cell Culture

Complete solutions to make your total upstream process robust and efficient, from R&D to full production scale, whether you are growing adherent cells for cell therapy or vaccine applications, or have large volume suspension cell culture requirements.

Complete solutions to make your total upstream process robust and efficient, from R&D to full production scale, whether you are growing adherent cells for cell therapy or vaccine applications, or have large volume suspension cell culture requirements.

Webinar: Thursday, April 27

Design, Characterization, and Scale-Up Strategy for a New Single-Use Production-Scale Bioreactor

Learn about the design, characterization and scale-up strategy for a new bioreactor and how it brings significant advantages to the upstream process for handling and process assurance, while maintaining optimal cell culture performance.

Design, Characterization, and Scale-Up Strategy for a New Single-Use Production-Scale Bioreactor

Learn about the design, characterization and scale-up strategy for a new bioreactor and how it brings significant advantages to the upstream process for handling and process assurance, while maintaining optimal cell culture performance.

Events and Webinars

Stay informed on the latest industry topics and trends, and be notified first of a range of innovations and solutions to continuously improve your processes. Click “Learn More” to subscribe to regular email updates.
Stay informed on the latest industry topics and trends, and be notified first of a range of innovations and solutions to continuously improve your processes. Click “Learn More” to subscribe to regular email updates.
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BioProcess International (BPI) European Summit 2017

Join Us at BPI on April 25-26, booths 43-44, to discover the recent advances in Continous Bioprocessing.

 

Presentations:

April 25 at 10am - Plenary Session

Significant Technology Advances Enabling Integrated Continuous Bioprocessing

Martin Smith, PhD, Chief Technology Officer

 

Continuous manufacturing has been established in several processing industries for many years providing improved economics, quality and flexibility over batch manufacturing operations. Until recently the adoption of continuous approaches in bioprocessing has been limited to perfusion cell culture with downstream processing unit operations and formulation taking place in batch mode with associated capacity limitations and poor facility utilization. With the development of specific enabling continuous technologies, combined with the inherent benefits of single-use approaches, it is possible for the biopharmaceutical industry embrace the continuous manufacturing paradigm and move towards integrated end to end continuous bioprocessing, resulting in a more efficient, agile and truly global production of biotherapeutics.

Presentation will discuss a range of continuous process-enabling technologies aimed at the key unit operations within the production of monoclonal antibodies and other recombinant proteins.

 

April 26 at 11.45am - Continuous Stream

Implementation Of An End-to-End Continuous BioProcessing Platform Using Novel Technologies

Peter Levison, Senior Marketing Director - Downstream Processing

 

A risk-based and data-driven overview of an integrated continuous bioprocessing platform highlights requirements, challenges and opportunities for product development, process monitoring, validation, control and automation. Cutting-edge technologies enable cost effective and reliable implementation of continuous bioprocessing. They include the Cadence™ Acoustic Separator, Cadence Inline Concentrators for single-pass TFF (SPTFF), the Cadence BioSMB multicolumn continuous chromatography using the KANEKA KanCapA™ sorbent and novel continuous diafiltration strategies.

 

April 26 at 2pm (30 minutes)- Viral Safety for Biologics

Novel Virus Filter Design To Overcome The Challenges Of Continuous Processing

Nigel Jackson, Principal Engineer R&D.

 

Recent studies in virus retentive filtration have changed our perception of the worst case scenarios for maximizing virus safety, with low flow and pressure interruptions increasing risk. We link fundamental understanding to filter design in order to open up the opportunity of optimal continuous processing at low flow.

 

Poster Session: 

April 25-26

Acoustic Wave Separation: A Scalable Disruptive Technology for Continuous Clarification of Fed Batch Cell Culture Prior to Capture Chromatography

 

Live Lab Tour

April 26 at 1.20pm

Don't forget to join us at The Live Lab Tour! An interactive session allowing you to gain practical insight in our latest technology hitting today's market.

 

Pall® Products Featured:

Cadence™ Acoustic Separator, Kleenpak® Presto Connectors, Pegasus™ Prime Virus Removal Filters

 

Just some of the reasons to see us at booths #43-44 or at presenter sessions throughout the event. We look forward to meeting you!

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Design, Characterization, and Scale-Up Strategy for a New Single-Use Production-Scale Bioreactor

What Will I Learn:

 

- Why a square cross-section brings significant advantages to the upstream process, for handling, process assurance, while maintaining optimal cell culture performance

- About the performance of a square-shaped bioreactor, in terms of mixing efficiency, mass transfer of oxygen (kLa), and CO2 stripping

- About applying system engineering principles toward bioreactor characterization, and how tech transfer methods are leveraged across designs, from the bench to production vessels

 

Learn More about this webinar

Register

About Pall Biopharmaceuticals

Pall products have played key development and manufacturing roles in life saving drugs that range from Ebola vaccines to cancer-curing monoclonal antibodies. Cutting-edge research demands high quality products that combine industry-leading effectiveness with high performance to increase profitability without sacrificing safety.

 

Our portfolio of products fit into integrated systems that reduce total cost of ownership by improving process economics. Reducing total cost of ownership is possible when customers partner with a supplier who is in tune with their unique challenges, whether for clinical or full manufacturing scale. Pall provides complete coverage from cell culture to formulation and filling. Our biopharmaceutical portfolio helps create life improving drugs faster and with lower upfront costs.

 

Just like the pharmaceutical industry, Pall continues to innovate. For example, our continuous processing technologies enable truly continuous production steps. Award-winning critical downstream processing (DSP) products like the Cadence Inline Concentrator (ILC) enables continuous concentration of the product, reducing shear damage and processing time and improving quality. Our disruptive Cadence Acoustic Separator in conjunction with a polishing depth filter will continuously remove cells and cell debris from cell culture in a closed system, without the need for centrifugation or primary depth filtration.  It reduces depth filtration and buffer use, and provides consistent solids reduction.

 

We will continue to evolve as the market changes. The rise of single-use facilities, process intensification, integrated unit operations, and continuous processing is improving facility efficiency and flexibility while simultaneously reducing footprint and processing times. Pall has the only bioprocessing portfolio on the market that can support biopharmaceutical manufacturers from upstream to downstream and into the final filling and finish phases. This single use, multiple solutions, outlook is an end-to-end solution for biomanufacturers seeking fully validated solutions and guaranteed scalable supply chain security.

 

No matter where your team is, Pall is there to support them. Pall Scientific and Laboratory Services have more than 30 years of experience with validation in the pharmaceutical industry. Global ISO9001 certified Centers of Excellence (CoE) are available to streamline scientific development and scale up.

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