From concept, through design, validation, and production across all areas of your business, Pall Biopharmaceuticals can help you to adapt to changing market conditions with innovative solutions. Whether that means developing a process for a new drug quickly, validating consistent results, ensuring quality control, delivering data, or making processing easier, faster, and better, Pall is ready to address your needs with intuitive technologies.  

  • Cell Culture

    Pall's Allegro™ single use cell culture technologies are complete solutions that make your total upstream process robust and efficient, from R&D to full production scale.

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  • Chromatography

    Cost-effective and innovative chromatographic purification platforms for today’s demanding applications and productivity goals.

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  • Continuous Processing

    Breakthrough technologies that enable integrated, process-scale continuous production of biotherapies in single-use formats.

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  • Depth Filtration

    Pall's high performance depth filtration solutions are the best choice for cell harvest, clarification, and prefiltration process steps.

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  • Filling Technologies

    Flexible single-use technologies protect your product at a critical manufacturing stage.

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  • Filtration

    An unmatched portfolio of traditional and single-use products with custom service support from R&D to clinical phases to production.

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  • Single-Use Solutions

    Single-use solutions that allow easy scale-up from the lab to full cGMP commercial production.

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  • Tangential Flow Filtration

    Pall's line of scalable TFF products range from single-use modules to cleanable cassettes, and from standard lab and benchtop systems to fully customizable process systems.

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  • Viral Clearance

    A range of filters and filter capsules optimized to provide robust, economic solutions for virus removal whatever your process requirements.

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Pall Biopharmaceuticals

INDUSTRY-LEADING PRODUCTS, SERVICES AND SUPPORT
Allegro™ MVP Single-Use System

Allegro™ MVP Single-Use System

A fully automated bioprocessing system, providing flexibility and improved productivity in upstream and downstream single-use processing.  Single-use technology continues to be adopted across many areas of bioprocessing. The use of automation provides additional benefits in manufacture such as consistency in product quality, reduced labor costs and reduction of operator errors.

Single-Use Solutions

Biomanufacturers need suppliers as innovative as they are.  Our unique single-use platform provides a comprehensive range of disposable process solutions from upstream, through downstream to formulation and filling. 

We have developed a unique approach, keeping the same materials of construction to allow easy scale-up from lab scale to full cGMP commercial operation, with the capability to provide the same robustness, reliability and batch records that you require to produce your drugs.

Biomanufacturers need suppliers as innovative as they are.  Our unique single-use platform provides a comprehensive range of disposable process solutions from upstream, through downstream to formulation and filling. 

We have developed a unique approach, keeping the same materials of construction to allow easy scale-up from lab scale to full cGMP commercial operation, with the capability to provide the same robustness, reliability and batch records that you require to produce your drugs.

We can serve our customers globally with strong technical support and a very robust and reliable supply chain with our global manufacturing platform meeting all the necessary quality requirements. We pride ourselves on the strong quality by design and ease-of-use attributes that we put into all our Allegro single-use systems, thus allowing our end users to meet consistently all the appropriate safety and regulatory requirements.    

We can serve our customers globally with strong technical support and a very robust and reliable supply chain with our global manufacturing platform meeting all the necessary quality requirements. We pride ourselves on the strong quality by design and ease-of-use attributes that we put into all our Allegro single-use systems, thus allowing our end users to meet consistently all the appropriate safety and regulatory requirements.    

Kleenpak® Presto Sterile Connector

Kleenpak® Presto Sterile Connector

Genderless sterile connections - Intuitive, reliable, secure.  The Kleenpak Presto sterile connector is the next generation in the Allegro™ range of single-use fluid handling and management devices. This new genderless connection allows for the permanent sterile connection of two fluid streams for a large range of biopharmaceutical applications.

Pall Biopharmaceuticals

INDUSTRY-LEADING PRODUCTS, SERVICES AND SUPPORT
Supor® EX Grade ECV Membrane Filter Cartridges

Supor® EX Grade ECV Membrane Filter Cartridges

Supor EX grade ECV filters are high capacity, high flow rate 0.2 μm sterilizing grade filters validated for the retention of B.diminuta (ATCC 19146) at a challenge level of 107 cfu per cm2 membrane. A unique polyethersulfone (PES) membrane pairing ensures Supor EX grade ECV filters deliver highly efficient filtration of cell harvest material, process intermediates, growth media, buffers and final bulk biological process fluids. Supor EX grade ECV filters also deliver unrivalled efficiency with more viscous process streams.

Filtration

Pall’s highly-developed membrane filter technology, with validated microbial removal claims are ideal for fluid sterilization or bioburden and particle control applications, whether upstream, downstream or at laboratory, pilot or production scale.

Filters are available with a wide range of membranes and in many different cartridge and capsule configurations to suit your needs. 

Many can be sterilized by gamma-irradiation for integration into Allegro™ Single Use Systems.    

Pall’s highly-developed membrane filter technology, with validated microbial removal claims are ideal for fluid sterilization or bioburden and particle control applications, whether upstream, downstream or at laboratory, pilot or production scale.

Filters are available with a wide range of membranes and in many different cartridge and capsule configurations to suit your needs. 

Many can be sterilized by gamma-irradiation for integration into Allegro™ Single Use Systems.    

Emflon® HTPFR Filter Cartridges

Emflon® HTPFR Filter Cartridges

Emflon HTPFR filter cartridges are specifically designed for the sterile filtration of air, gas and vent service in critical, high temperature and ozonated-water venting applications. They can also be considered for use in oxygen-enriched air applications in the biopharmaceutical and biotechnology industries (see Pall publication USTR2311a). High-temperature applications include autoclave, fermentation inlet air, aseptic packaging/blow-fill-seal and hot Water For Injection (WFI) tank vents. These filters incorporate a double-layer (0.2 μm) of inherently hydrophobic, Pall-manufactured polytetrafluoroethylene (PTFE) membrane. The polypropylene hardware is specially formulated with protective anti-oxidants and the filter's support and drainage layers are made of polyphenyl sulphide polymer. Oxidation-resistant filter components allow extended use in air/vent service up to 100 °C and for shorter periods up to 120 °C.

Webinars and Events

Our webinars keep you informed on the latest Pall® products and technologies, plus current industry topics, the latest trends and a range of innovations and solutions to help continuously improve your processes. Click the button below to subscribe to our email updates on webinars and events.
Our webinars keep you informed on the latest Pall® products and technologies, plus current industry topics, the latest trends and a range of innovations and solutions to help continuously improve your processes. Click the button below to subscribe to our email updates on webinars and events.
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Interphex 2017

Implement cost effective technologies and gain insight and knowledge at this large industry exhibition that features Pall innovations in core filter products, single-use and continuous biomanufacturing breakthrough technologies.

 

Equipment/Products on Display:

  • Cadence™ Acoustic Separator
  • Cadence BioSMB Process System and Cadence BioSMB Development System
  • Kleenpak® Presto Sterile Connectors
  • Pegasus™ Prime and with Pegasus Protect Virus Removal Filter Membrane Capsules and Cartridges
  • Development scale single-use TFF systems, featuring the Allegro™ CM150 Single-Use Tangential Flow Filtration System
  • iCELLis® Bioreactors
  • Allegro Unison hMSCs and Media
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Accelerating The Development of Regenerative Therapies: Large Scale Expansion of Human Mesenchymal Stem Cells

What Will I Learn:

 

- How Allegro™ Unison hMSCs and bioprocess media, and SoloHill® microcarriers and Pall® PadReactor systems enable large-scale hMSC expansion

- Culture protocol for 200-fold hMSC expansion, within 10 days, in a single-use, fed-batch scalable manufacturing platform.

- How regenerative medicine and cell therapy developers can rapidly and economically move towards producing tens of billions to >1 trillion high quality hMSCs for product development programs in single-use bioreactors

 

Learn More about this webinar

Register

About Pall Biopharmaceuticals

Pall products have played key development and manufacturing roles in life saving drugs that range from Ebola vaccines to cancer-curing monoclonal antibodies. Cutting-edge research demands high quality products that combine industry-leading effectiveness with high performance to increase profitability without sacrificing safety.

 

Our portfolio of products fit into integrated systems that reduce total cost of ownership by improving process economics. Reducing total cost of ownership is possible when customers partner with a supplier who is in tune with their unique challenges, whether for clinical or full manufacturing scale. Pall provides complete coverage from cell culture to formulation and filling. Our biopharmaceutical portfolio helps create life improving drugs faster and with lower upfront costs.

 

Just like the pharmaceutical industry, Pall continues to innovate. For example, our continuous processing technologies enable truly continuous production steps. Award-winning critical downstream processing (DSP) products like the Cadence Inline Concentrator (ILC) enables continuous concentration of the product, reducing shear damage and processing time and improving quality. Our disruptive Cadence Acoustic Separator in conjunction with a polishing depth filter will continuously remove cells and cell debris from cell culture in a closed system, without the need for centrifugation or primary depth filtration.  It reduces depth filtration and buffer use, and provides consistent solids reduction.

 

We will continue to evolve as the market changes. The rise of single-use facilities, process intensification, integrated unit operations, and continuous processing is improving facility efficiency and flexibility while simultaneously reducing footprint and processing times. Pall has the only bioprocessing portfolio on the market that can support biopharmaceutical manufacturers from upstream to downstream and into the final filling and finish phases. This single use, multiple solutions, outlook is an end-to-end solution for biomanufacturers seeking fully validated solutions and guaranteed scalable supply chain security.

 

No matter where your team is, Pall is there to support them. Pall Scientific and Laboratory Services have more than 30 years of experience with validation in the pharmaceutical industry. Global ISO9001 certified Centers of Excellence (CoE) are available to streamline scientific development and scale up.

ASK BIOPHARMACEUTICALS A QUESTION

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